Depletion of MHC supertype during domestication can compromise immunocompetence
نویسندگان
چکیده
منابع مشابه
Evolution during Domestication
Domestication is a genetic selection process exerted – consciously or unconsciously – by humans to adapt wild plants andanimals to cultivation andherding, respectively. Because of this process, major crops and domesticated breeds arose,whichwere not only easier to cultivate or herd but also more appealing to consume or process for further uses. During domestication, plants and animals are subje...
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Despite being probably one of the most studied topics in Evolutionary Biology, the mechanisms of maintenance of major histocompatibility complex (MHC) diversity in vertebrates remain also one of the most debated topics [1]. Ellison et al. [2] studied MHC class I diversity of a selfing Kryptolebias marmoratus population by clustering alleles in supertypes grouped by their physico-chemical simila...
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It has been hypothesized that reproductive isolation should facilitate evolution under domestication. However, a systematic comparison of reproductive barrier strength between crops and their progenitors has not been conducted to test this hypothesis. Here, we present a systematic survey of reproductive barriers between 32 economically important crop species and their progenitors to better unde...
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Ly49 recognition of MHC class I (MHC I) can be allele specific. However, the site of interaction on MHC I consists of highly conserved solvent-exposed amino acids, leaving it unclear how allele specificity occurs. In examining the specificity of mouse and rat Ly49, we noticed that MHC I ligands for mouse Ly49G and W, and the rat Ly49i2, typically share the HLA-B7 supertype, defined by a B-pocke...
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ژورنال
عنوان ژورنال: Molecular Ecology
سال: 2020
ISSN: 0962-1083,1365-294X
DOI: 10.1111/mec.15763